SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000096
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000097
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd3eem1(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18021
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190017
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00079
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200277
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018
Research Application：tumor research；inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00101
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200258
Research Application：tumor research；inmmue therapy；drug screening
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