SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Gdf15tm1(hGDF15)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220151
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Strain Name：C57BL/6JSmo-H2-D1tm1(hHLA-A2*01)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-233927
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Strain Name：C57BL/6JSmo-Icostm1(hICOS)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00052
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Icostm2(hICOS)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190030
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cJSmo-Icostm1(hICOS)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000046
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Icosltm1(hICOSLG) Icostm1(hICOS)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18018
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Icosltm1(hICOSLG) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00095
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Icosltm3(hICOSLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000068
Research Application：Immunotherapy,drug screening
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Strain Name：B6;129S-Ido1tm1(hIDO1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00061
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Il1rl1tm4(hIL1RL1)Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-232112
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