SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00137
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd274tm1(hPD-L1)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00111
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Cd274tm1(hCD274)Siglec15tm1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Tmem173tm1(hTMem173)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000105
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18013
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190056
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Selplgtm1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046
Research Application：Immunotherapy,cancer research,drug screening
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