SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18013
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190056
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Selplgtm1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Selplgtm2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Pvrigtm1(hPVRIG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210008
Research Application：drug screening
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Strain Name：C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000061
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Siglec15tm1(hSIGLEC15)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190037
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Siglec15tm2(hSIGLEC15) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200001
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Siglecetm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983
Research Application：Immunotherapy, drug screening
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