Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Sirpatm2(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000089
Research Application:Immunotherapy,drug screening
mouse
Strain Name:C57BL/6JSmo-Tmem173tm1(hTMem173)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000104
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1) Tigittm1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00104
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Tigittm1(hTIGIT) Havcr2tm1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190029
Research Application:Immune-related
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Havcr2tm1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00103
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Tlr9 tm1(hTLR9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190023
Research Application:Immune-related
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000098
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000092
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Cd274tm1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200260
Research Application:umor research;inmmue therapy;drug screening
mouse
Strain Name:C57BL/6JSmo-Cd274tm1(hPD-L1)Cd40tm1(hCD40)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18024
Research Application:Immunotherapy,cancer research,drug screening
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