SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Selplgtm2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Pvrigtm1(hPVRIG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210008
Research Application：drug screening
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Strain Name：C57BL/6JSmo-Siglecgtm1(hSIGLEC10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000061
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Siglec15tm1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190037
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cJSmo-Siglec15tm2(hSIGLEC15) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200001
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Siglecetm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983
Research Application：Immunotherapy, drug screening
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Strain Name：C57BL/6JSmo-Siglecftm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210033
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Siglecetm1(hSIGLEC9)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225072
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18015
Research Application：Immunotherapy,drug screening
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Strain Name：BALB/cJSmo-Sirpatm(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210369
Research Application：inmmue therapy;drug screening
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