SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000111
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cJSmo-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210020
Research Application：tumor research；inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Cd5tm(hCD5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220579
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Strain Name：C57BL/6JSmo-Cd52tm1(hCD52)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000058
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Cd55tm(hCD55)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215008
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Strain Name：C57BL/6JSmo-Cd6tm(hCD6)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220210
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Strain Name：C57BL/6JSmo-Cd70tm(hCD70)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220514
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Strain Name：C57BL/6JSmo-Nt5etm3(NT5E)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200009
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd74tm1(hCD74)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000082
Research Application：Immunotherapy,drug screening
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