SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Cd40tm1(hCD40)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406
Research Application：inmmue therapy; drug screening
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Strain Name：C57BL/6JSmo-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Research Application：Immunotherapy,drug screening
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Strain Name：BALB/cJSmo-Cd40lgtm1(hCD40L)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000052
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Cd44tm(hCD44)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215003
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Strain Name：C57BL/6JSmo-Il3tm1(hIL3)Csf2tm1(CSF2)Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200270
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368
Research Application：inmmue therapy;drug screening
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358
Research Application：inmmue therapy；drug screening
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Strain Name：BALB/cJSmo-Pdcd1tm(hPDCD1)Cd274tm(hPD-L1)Sirpatm4(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143
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Strain Name：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47) Pdcd1tm1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000090
Research Application：Immune-related
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