hCD5(2)

Nomenclature

C57BL/6Smoc-Cd5tm(hCD5)Smoc

Cat. NO.

NM-HU-220579

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cd5

Synonyms

Ly-1; Ly-A; Ly-12; Lyt-1

NCBI ID

12507

MGI ID

88340

Ensembl ID

ENSMUSG00000024669

Pubmed

Cd5

Human Ortholog

CD5

Model Description

The endogenous mouse Cd5 gene was replaced by human CD5 gene.

Validation Data

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Fig.1 Detection of CD5 expression in thymus by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1 (mCd5);

Homozygous: only one band at 350 bp with primers F2/R2 (hCD5).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of hCD5 expression in T cells and B cells in Blood in hCD5(2) KI mice.

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Fig.3 Detection of hCD5 expression in T cells and B cells in Spleen in hCD5(2) KI mice.

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Fig.4 Analysis of leukocytes cell subpopulation in Blood and spleen.

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