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Models

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Mice

Abcb4-KO(FVB)

Strain Name：FVB-Abcb4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200584
Validation Data：Presence

Exon 3-4 of Abcb4 gene was deleted to generate Abcb4 knockout mice.

Mice

Calb2-IRES-Cre

Strain Name：C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200102
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

hTNFRSF1A

Strain Name：C57BL/6Smoc-Tnfrsf1atm(hTNFRSF1A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215017

The endogenous mice Tnfrsf1a gene was replaced by human TNFRSF1A gene.

Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9tm2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075
Validation Data：Presence

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hCD40L

Strain Name：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Validation Data：Presence

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

hCCR8

Strain Name：C57BL/6Smoc-Ccr8tm1(hCCR8) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190053
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(2)(Stock No.NM-HU-2000054) mice function similarly to hCCR8 mice,for more detailed information please contact our technical advisor.

Mice

hCD40(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40tm1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000047
Validation Data：Presence

The endogenous mouse Cd40 gene was replaced by human CD40 gene.

Mice

hPD-L2

Strain Name：C57BL/6Smoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190050
Validation Data：Presence

将小鼠Pdcd1lg2基因全部或者部分替换为人源PDCD1LG2，从而表达人或人鼠嵌合PDCD1LG2蛋白，取代小鼠内源Pdcd1lg2蛋白的表达 hPD-L2.

Mice

Aqp5-2A-CreERT2

Strain Name：C57BL/6Smoc-Aqp5em1(2A-CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200313
Validation Data：Presence

2A-CreERT2-Wpre-pA expression cassette was knocked into the Aqp5 gene stop codon site.

Mice

hCD20

Strain Name：C57BL/6Smoc-Ms4a1tm2(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190068

The endogenous mouse Cd20(Ms4a1) gene was replaced by human CD20 gene. While hCD20(2)(Stock No.NM-HU-200114) mice function similarly to hCD20 mice,for more detailed information please contact our technical advisor.

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