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Models

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Mice

Calb2-IRES-Cre

Strain Name：C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200102
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200319
Publications：1piece

A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

hTNFRSF1A

Strain Name：C57BL/6Smoc-Tnfrsf1atm(hTNFRSF1A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215017

The endogenous mice Tnfrsf1a gene was replaced by human TNFRSF1A gene.

Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9tm2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hCD40L

Strain Name：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Validation Data：Presence

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

hCCR8

Strain Name：C57BL/6Smoc-Ccr8tm1(hCCR8) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190053
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(2)(Stock No.NM-HU-2000054) mice function similarly to hCCR8 mice,for more detailed information please contact our technical advisor.

Mice

hCD40(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40tm1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000047
Validation Data：Presence

The endogenous mouse Cd40 gene was replaced by human CD40 gene.

Mice

hGPR75

Strain Name：C57BL/6Smoc-Gpr75tm1(hGPR75)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215056
Validation Data：Presence

The endogenous mouse Gpr75 gene was replaced by human GPR75 gene.

Mice

hPD-L2

Strain Name：C57BL/6Smoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190050
Validation Data：Presence

将小鼠Pdcd1lg2基因全部或者部分替换为人源PDCD1LG2，从而表达人或人鼠嵌合PDCD1LG2蛋白，取代小鼠内源Pdcd1lg2蛋白的表达 hPD-L2.

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