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Models

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Mice

CD8a-IRES-Luc-2A-tdTomato（BALB/c）

Strain Name：BALB/cJSmo-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200208
Validation Data：Presence

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

Abcb4-KO(FVB)

Strain Name：FVB-Abcb4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200584
Validation Data：Presence

Exon 3-4 of Abcb4 gene was deleted to generate Abcb4 knockout mice.

Mice

hPCSK9

Strain Name：C57BL/6JSmo-Pcsk9tm2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

Alb-2A-HSVTK(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-HSVTK)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215046

2A-HSVTK expression cassette was knocked into the Alb gene.

Mice

Axin2-CreERT2

Strain Name：C57BL/6JSmo-Axin2em1(CreERT2-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200109
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

Itgam-IRES-hCD89/hIGHA1

Strain Name：C57BL/6JSmo-Itgamtm1(IRES-hCD89-WPRE-polyA)sμtm1(hIGHA1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210412
Validation Data：Presence

Itgam-IRES-hCD89(NM-KI-200063) was crossed with hIGHA1(NM-HU-2000086) to generate Itgam-IRES-hCD89/hIGHA1 mice.

Mice

Adipoq-IRES-Dre

Strain Name：C57BL/6JSmo-Adipoqem(IRES-Dre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225055

IRES-Dre expression cassette was knocked into the Adipoq gene .

Mice

hTLR9/hOX40

Strain Name：C57BL/6JSmo-Tlr9tm1(hTLR9)Tnfrsf4tm3(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Alb-DreERT2

Strain Name：C57BL/6JSmo-Albem1(Kozak-DreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200076

A Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Alb gene start codon site.

Mice

hCD20

Strain Name：C57BL/6JSmo-Ms4a1tm2(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190068

The endogenous mouse Cd20(Ms4a1) gene was replaced by human CD20 gene. While hCD20(2)(Stock No.NM-HU-200114) mice function similarly to hCD20 mice,for more detailed information please contact our technical advisor.

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