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Models

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Mice

hTSLP

Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000064

The endogenous mouse Tslp gene was replaced by human TSLP gene.

Mice

hCD24/hSIGLEC10

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210367

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061）to generate hCD24/hSIGLEC10 mice.

Mice

hTFR1

Strain Name：C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215059

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

Abcg2-KO

Strain Name：C57BL/6Smoc-Abcg2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18013

Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.

Mice

Calb2-IRES-Cre

Strain Name：C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200102

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

hSEMA4D

Strain Name：C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9em1(hTLR9)Tnfrsf4em3(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hVEGFA(2)

Strain Name：C57BL/6Smoc-Vegfaem1(hVEGFA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204984

The endogenous mice Vegfa gene was replaced by human VEGFA gene. While hVEGFA(Stock No.NM-HU-2000028) mice function similarly to hVEGFA(2) mice,for more detailed information please contact our technical advisor.

Mice

Arc-CreERT2

Strain Name：C57BL/6Smoc-Arcem1(CreERT2-SV40-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200101

A CreERT2 expression cassette was knocked into the Arc gene start codon site.

Mice

hCCR8/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210435

hCCR8(NM-HU-190053) was crossed with hCTLA4(NM-HU-00014) to generate hCCR8/hCTLA4 mice.

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