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Models

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Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4tm3(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCSF1/hCSF1R(BALB/c)

Strain Name：BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rtm3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220016
Validation Data：Presence

The endogenous mouse Csf1 and Csf1r genes was replaced respectively by human CSF1 and CSF1R genes.

Mice

hSEMA4D

Strain Name：C57BL/6Smoc-Sema4dtm1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117
Validation Data：Presence

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

hVSIG4

Strain Name：C57BL/6Smoc-Vsig4tm1(hVSIG4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210004
Validation Data：Presence

The endogenous mice Vsig4 gene was replaced by human VSIG4 gene

Mice

Akt1-KO

Strain Name：C57BL/6Smoc-Akt1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190741

Exon 2 of Akt1 gene was deleted to generate Akt1 knockout mice.

Mice

hCCR8(2)/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8tm3(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220074
Validation Data：Presence

hCTLA4 (NM-HU-00014) mice were crossed with hCCR8(2) (NM-HU-2000054) mice to generate hCCR8(2)/hCTLA4 mice．

Mice

hCD180

Strain Name：C57BL/6Smoc-Cd180tm1(hCD180)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210006
Validation Data：Presence

The endogenous mice Cd180 gene was replaced by human CD180 gene

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225087
Validation Data：Presence

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18015
Validation Data：Presence

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.

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