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Models

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Mice

hTFR1

Strain Name：C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215059
Validation Data：Presence

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19tm1(hCD19)Cd3etm1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027
Validation Data：Presence

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hANGPTL3(3)

Strain Name：C57BL/6Smoc-Angptl3tm2(hANGPTL3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210037
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

Mice

hLAG3

Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hIL9

Strain Name：C57BL/6Smoc-Il9tm3(hIL9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18029
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene .

Mice

hCSF1/hCSF1R(2)

Strain Name：C57BL/6Smoc-Csf1tm2(CSF1)Csf1rtm3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200273

hCSF1(NM-HU-190043) was crossed with hCSF1R(NM-HU-190074)to generate hCSF1/hCSF1R(2) mice.

Mice

hCD160

Strain Name：C57BL/6Smoc-Cd160tm1(CD160)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190057

The endogenous mouse Cd160 gene was replaced by human CD160 gene.

Mice

hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00079
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

Alb-2A-HSVTK(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-HSVTK)Smoc
Strain State：Developing | Cat. NO.：NM-KI-215046

2A-HSVTK expression cassette was knocked into the Alb gene.

Mice

hVSIG4

Strain Name：C57BL/6Smoc-Vsig4tm1(hVSIG4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210004
Validation Data：Presence

The endogenous mice Vsig4 gene was replaced by human VSIG4 gene

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