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Models

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Mice

hAR

Strain Name：C57BL/6Smoc-Artm2(hAR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225061
Validation Data：Presence

The endogenous mouse Ar gene was replaced by human AR gene.

Mice

hTFR1

Strain Name：C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215059
Validation Data：Presence

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

R26-CAG-RSR-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-RSR-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200191

This mouse was obtained by crossing R26-(CAG-LSL-RSR-tdTomato-2A-DTR) mice with systemic Cre mice.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19tm1(hCD19)Cd3etm1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027
Validation Data：Presence

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Cd19-Cre-IRES-tdTomato

Strain Name：C57BL/6Smoc-Cd19em1(iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200061
Validation Data：Presence

A iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA expression cassette was knocked into the Cd19 gene.

Mice

hLAG3

Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hCSF1/hCSF1R(2)

Strain Name：C57BL/6Smoc-Csf1tm2(CSF1)Csf1rtm3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200273

hCSF1(NM-HU-190043) was crossed with hCSF1R(NM-HU-190074)to generate hCSF1/hCSF1R(2) mice.

Mice

hCD160

Strain Name：C57BL/6Smoc-Cd160tm1(CD160)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190057

The endogenous mouse Cd160 gene was replaced by human CD160 gene.

Mice

Alb-2A-HSVTK(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-HSVTK)Smoc
Strain State：Developing | Cat. NO.：NM-KI-215046

2A-HSVTK expression cassette was knocked into the Alb gene.

Mice

Itgam-IRES-hCD89/hIGHA1

Strain Name：C57BL/6Smoc-Itgamtm1(IRES-hCD89-WPRE-polyA)sμtm1(hIGHA1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210412
Validation Data：Presence

Itgam-IRES-hCD89(NM-KI-200063) was crossed with hIGHA1(NM-HU-2000086) to generate Itgam-IRES-hCD89/hIGHA1 mice.

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