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Models

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Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

hB2M-HLA A2.1(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-D1em1(hB2M-HLA A2.1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-225089

The endogenous mouse H2-D1 gene was replaced by human B2M-HLA A2.1 gene.

Mice

Epcam-2A-CreERT2

Strain Name：C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00084

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

Map2-2A-CreERT2

Strain Name：C57BL/6Smoc-Map2em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00037

Map2 is a marker of mature neurons. A 2A-CreERT2 cassette was inserted before the translational termination site of the Map2 locus.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000060

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

hCB1

Strain Name：C57BL/6Smoc-Cnr1em1(hCB1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225027

The endogenous mouse Cnr1 gene was replaced by human CB1 gene.

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

Scgb3a2-IRES-Cre

Strain Name：C57BL/6Smoc-Scgb3a2em1(IRES-Cre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210127

IRES-Cre-polyA expression cassette was knocked into the Scgb3a2 gene.

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