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Models

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Mice

Epcam-2A-CreERT2

Strain Name：C57BL/6JSmo-Epcamem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00084
Validation Data：Presence

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

Tmem119-2A-DTRGFP

Strain Name：C57BL/6JSmo-Tmem119em4(P2A-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200235

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

Fcgr1-KO

Strain Name：C57BL/6JSmo-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

Cd19-IRES-EGFP-Luc

Strain Name：C57BL/6JSmo-Cd19em1(IRES-EGFP-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200058

A IRES-EGFP-Luci expression cassette was knocked into the Cd19 gene stop codon site.

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6JSmo-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

hPD-1/hPD-L1/hOX40

Strain Name：C57BL/6JSmo-Tnfrsf4tm3(hTNFRSF4)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00122

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

Mice

hCTLA-4

Strain Name：C57BL/6JSmo-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

hTNFR2

Strain Name：C57BL/6JSmo-Tnfrsf1btm2(hTNFRSF1B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190010
Validation Data：Presence

The endogenous mouse Tnfrsf1b gene was replaced by human TNFRSF1B gene.

Mice

hCALCRL

Strain Name：C57BL/6JSmo-Calcrltm1(hCALCRL)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225031
Validation Data：Presence

The endogenous mouse Calcrl gene was replaced by human CALCRL gene.

Mice

hB7H4(2)

Strain Name：C57BL/6JSmo-Vtcn1tm2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

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