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Mice

Braf-Flox

Strain Name：C57BL/6Smoc-Brafem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200073

These mice carry loxP sites flanking exon 5 of Braf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Braf gene.

Mice

A1bg-Flox

Strain Name：C57BL/6Smoc-A1bgem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253740

These mice carry loxP sites flanking exon 1-5 of A1bg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1bg gene.

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2tm4(hTRem2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083
Validation Data：Presence

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1tm2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

A2m-Flox

Strain Name：C57BL/6Smoc-A2mem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253744

These mice carry loxP sites flanking exon 2-4 of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

Mice

Muc2-2A-CreERT2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Muc2em1(2A-CreERT2-tdTomato-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200301
Validation Data：Presence

2A-CreERT2-tdTomato-Wpre-pA expression cassette was knocked into the Muc2 gene stop codon site.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565
Validation Data：Presence

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

Mice

HBV-Tg

Strain Name：B6.Cg-Tg(HBV)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00003
Validation Data：Presence

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

Mice

B2m-KO

Strain Name：C57BL/6Smoc-B2mem3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18021
Validation Data：Presence

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

BALB/c Nude

Strain Name：BALB/cAnSmoc-Foxn1nu/Smoc
Strain State：Repository Live | Cat. NO.：SM-014
Validation Data：Presence

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

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