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Models

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Mice

NVG-hIL15

Strain Name:NOD-PrkdcscidIl2rgem1Il15(hIL15)Smoc
Strain State:Repository Live | Cat. NO.:GM-NVG-210001
Validation Data:Presence

The endogenous mice Il15 gene was replaced by human IL15 gene.

Mice

hCD27(2)

Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190035
Validation Data:Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093)have been pulled from shelves for some reasons.

Mice

Csf1r-IRES-Cre

Strain Name:C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190026
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.

Mice

Ar-Flox

Strain Name:B6;129S-Artm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-00110
Publications:2piece

These mice carry loxP sites flanking exon 2 of Ar gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ar gene.

Mice

NOD SCID

Strain Name:NOD.Cg-Prkdcscid/NifdcSmoc
Strain State:Repository Live | Cat. NO.:SM-019
Validation Data:Presence

The strain was developed on background of non-obese diabetic (NOD) mouse with spontaneous scid mutation. NOD SCID mouse, insusceptible to diabetes, possesses reduced activity of T cells and B cells, and defect in innate immunity.NOD SCID mouse is compatible with a wider range of engraftment of cell lines in comparison with nude mouse; And it is broadly applied to construction of PDX models. However, due to a short life span(8-9 months) caused by lethal thymic lymphomas, it is unsuitable for long-term in vivo assays.

Mice

Pdx1-2A-CreERT2

Strain Name:C57BL/6Smoc-Pdx1em1(Avi tag-2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18042
Validation Data:Presence

An Avi tag-2A-CreERT2 cassette was inserted at the Pdx1 gene stop codon site .

Mice

Zbtb46-IRES-Cre

Strain Name:C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200096
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site.

Mice

Apc-Flox

Strain Name:C57BL/6Smoc-Apctm2(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

hOX40

Strain Name:C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00041
Validation Data:Presence

The endogenous mouse Tnfrsf4(Ox40) gene was replaced by human TNFRSF4(OX40) gene. While hOX40(2)(Stock No.NM-HU-00078) mice function similarly to hOX40 mice,for more detailed information please contact our technical advisor.

Mice

Muc2-2A-CreERT2-IRES-tdTomato

Strain Name:C57BL/6Smoc-Muc2em1(2A-CreERT2-tdTomato-Wpre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200301
Validation Data:Presence

2A-CreERT2-tdTomato-Wpre-pA expression cassette was knocked into the Muc2 gene stop codon site.

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