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Models

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Mice

hB7H3/hPD-1

Strain Name:C57BL/6Smoc-Cd276em2(hCD276)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210349

hB7-H3(NM-HU-00107) was crossed with hPD-1(NM-HU-00015) to generate hB7H3/hPD-1 mice.

Mice

Cd19-Cre-IRES-tdTomato

Strain Name:C57BL/6Smoc-Cd19em1(iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200061

A iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA expression cassette was knocked into the Cd19 gene.

Mice

hALB

Strain Name:C57BL/6Smoc-Albem3(ALB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200003

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

Rag2-KO

Strain Name:C57BL/6Smoc-Rag2em2Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

hB7H4

Strain Name:C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hCD3E

Strain Name:C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00114

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

Epcam-2A-CreERT2

Strain Name:C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00084

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

HLA-A2.22/B2M

Strain Name:C57BL/6Smoc-H2-D1em1(hB2M/HLA-A2)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

Braf-Flox-V600E

Strain Name:C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190053

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

hCCR8(BALB/c)

Strain Name:BALB/cAnSmoc-Ccr8em1(hCCR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000048

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

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