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Models

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Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080
Validation Data：Presence

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6Smoc-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

NVG-hIL15

Strain Name：NOD-PrkdcscidIl2rgem1Il15(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：GM-NVG-210001
Validation Data：Presence

The endogenous mice Il15 gene was replaced by human IL15 gene.

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

Mice

hPD-1/hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00122

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000060
Validation Data：Presence

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

Ccr2-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Ccr2em1(IRES-DTRGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210102
Validation Data：Presence

IRES-DTRGFP expression cassette was knocked into the Ccr2 gene .

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

hVISTA

Strain Name：C57BL/6Smoc-Vsirtm1(hVSIR)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00118
Validation Data：Presence

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hTNFR2

Strain Name：C57BL/6Smoc-Tnfrsf1btm2(hTNFRSF1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190010
Validation Data：Presence

The endogenous mouse Tnfrsf1b gene was replaced by human TNFRSF1B gene.

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