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Mice

hB7H3/hPD-1

Strain Name：C57BL/6JSmo-Cd276tm2(hCD276)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210349

hB7-H3(NM-HU-00107) was crossed with hPD-1(NM-HU-00015) to generate hB7H3/hPD-1 mice.

Mice

hALB

Strain Name：C57BL/6JSmo-Albtm3(ALB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200003
Validation Data：Presence

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

hBTLA(2)

Strain Name：C57BL/6JSmo-Btlatm2(hBTLA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190040
Validation Data：Presence

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hCD40

Strain Name：C57BL/6JSmo-Cd40tm1(hCD40) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00076
Validation Data：Presence

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

hCD3E

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Validation Data：Presence

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

Aplnr-2A-DreERT2

Strain Name：C57BL/6JSmo-Aplnrem1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00132
Publications：1piece

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

Mice

Abcg2-KO

Strain Name：C57BL/6JSmo-Abcg2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18013
Validation Data：Presence

Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.

Mice

Cd19-IRES-DTRGFP

Strain Name：C57BL/6JSmo-Cd19em2(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190042
Validation Data：Presence

A IRES-DTREGFP expression cassette was knocked into the Cd19 gene stop codon site.

Mice

A2m-KO

Strain Name：C57BL/6JSmo-A2mem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190549

Exon 4 of A2m gene was deleted to generate A2m knockout mice.

Mice

Akt1-KO

Strain Name：C57BL/6JSmo-Akt1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190741

Exon 2 of Akt1 gene was deleted to generate Akt1 knockout mice.

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