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Models

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Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name：C57BL/6Smoc-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200154

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

hVISTA

Strain Name：C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00118

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hCSF1

Strain Name：C57BL/6Smoc-Csf1tm2(CSF1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190043

The endogenous mouse Csf1 gene was replaced by human CSF1 gene.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

Procr-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Procrem5(CreERT2-P2A-tdtomato-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200227

A CreERT2-P2A-tdtomato-Wpre-pA expression cassette was knocked into the Procr gene start codon site.

Mice

Aicda-Cre

Strain Name：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200160

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

hSTING

Strain Name：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190036

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000060

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

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