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Models

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Mice

Agrp-Dre

Strain Name：C57BL/6JSmo-Agrpem(Kozak-Dre-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220331

Kozak-Dre-WPRE-pA expression cassette was knocked into the Agrp gene start codon site.

Mice

hTIGIT

Strain Name：C57BL/6JSmo-Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

A1bg-KO

Strain Name：C57BL/6JSmo-A1bgem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200806

Exon 1-5 of A1bg gene was deleted to generate A1bg knockout mice.

Mice

R26-CAG-RSR-tdTomato-2A-DTR

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(CAG-RSR-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200191

This mouse was obtained by crossing R26-(CAG-LSL-RSR-tdTomato-2A-DTR) mice with systemic Cre mice.

Mice

Ccr2-IRES-DTRGFP

Strain Name：C57BL/6JSmo-Ccr2em1(IRES-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210102
Validation Data：Presence

IRES-DTRGFP expression cassette was knocked into the Ccr2 gene .

Mice

hTFR1

Strain Name：C57BL/6JSmo-Tfrctm1(hTFRC)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215059
Validation Data：Presence

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

Upk3a-2A-GFPCre

Strain Name：C57BL/6JSmo-Upk3aem1(2A-EGFP-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210003

2A-EGFP-Cre expression cassette was knocked into the Upk3a gene .

Mice

Adk-KO

Strain Name：C57BL/6JSmo-Adkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201237

Exon 4 of Adk gene was deleted to generate Adk knockout mice.

Mice

hTLR9

Strain Name：C57BL/6JSmo-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016
Validation Data：Presence

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

A2m-Flox

Strain Name：C57BL/6Smoc-A2mem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253744

These mice carry loxP sites flanking exon 2-4 of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

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