Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mice
Strain Name:C57BL/6Smoc-Trex1em1D18NSmoc
Strain State:Repository Live | Cat. NO.:NM-KI-231599
Mice
Strain Name:C57BL/6Smoc-Trp53tm(Frt-Stop-Frt-R270H)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-210364
Mice
Strain Name:C57BL/6Smoc-Trp53tm7(R270H-flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200186
Research Application:Cancer research
Mice
Strain Name:C57BL/6Smoc-Trp53em4(R172H)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18028
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Trp53em4(R172H)Krasem4(LSL-G12D)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-230388
Mice
Strain Name:C57BL/6Smoc-Trp53em(R245W)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225098
Mice
Strain Name:C57BL/6Smoc-Trp53em3(R270H)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18027
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Trpm2em(D1066A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215101
Mice
Strain Name:C57BL/6Smoc-Trpm8em1(S966A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190101
Research Application:Cation channel
Mice
Strain Name:B6;129S-Ttrtm1(G103R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00134
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