Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

mouse	Clcc1-K298A Strain Name：C57BL/6JSmo-Clcc1^tm1K298A^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-234160
mouse	Col4a5-R373X Strain Name：C57BL/6JSmo-Col4a5^{em1(R373X)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200296
mouse	Col4a5-R471X Strain Name：C57BL/6JSmo-Col4a5^{em1(R471X)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-200183
mouse	Cpa1-N256K Strain Name： Strain State： \| Cat. NO.：
mouse	Crbn-I391V Strain Name：C57BL/6JSmo-Crbn^{em1(I391V)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-200331
mouse	Crbn-I391V/Rag2-KO Strain Name：C57BL/6JSmo-Crbne^m1(I391V)Rag2^em2Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KI-210398
mouse	Crbn-V380E Strain Name：C57BL/6JSmo-Crbn^{em(V380E)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-210370
mouse	Dhtkd1-Y485X Strain Name：B6;129S-Dhtkd1^tm1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KI-00005
mouse	Dmd-Q995X Strain Name：C57BL/6JSmo-Dmd^{em1(Q995X)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-18026 Disease Connection：Duchenne muscular dystrophy
mouse	Dnmt3a-LSL-R878H Strain Name：C57BL/6JSmo-Dnmt3a^{tm1(LSL-R878H)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-230147

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