Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.
|
|
Strain Name：C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18026
Disease Connection：Duchenne muscular dystrophy
|
|
|
|
Strain Name：C57BL/6Smoc-Dnmt3atm1(LSL-R878H)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-230147
|
|
|
|
Strain Name：C57BL/6Smoc-Erbb4em1(I712M)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200283
|
|
|
|
Strain Name：C57BL/6Smoc-Erbb4em1(R1259W)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200282
|
|
|
|
Strain Name：C57BL/6Smoc-Erbb4em1(R927Q)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200281
|
|
|
|
Strain Name：C57BL/6Smoc-Fbn1em1(C1041G)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200303
Disease Connection：Marfan syndrome
|
|
|
|
Strain Name：C57BL/6Smoc-Fgf23em1(R176Q)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200248
Disease Connection：hypophosphatemic rickets
|
|
|
|
Strain Name：C57BL/6Smoc-Fgfr3em1G374RSmoc
Strain State：Repository Live | Cat. NO.：NM-KI-232354
|
|
|
|
Strain Name：C57BL/6Smoc-Fgfr3em1N535KSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232380
|
|
|
|
Strain Name：C57BL/6Smoc-Fgfr3em1P244RSmoc
Strain State：Developing | Cat. NO.：NM-KI-240342
|
