Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

mouse
Strain Name:C57BL/6JSmo-Ttrtm1(hTTR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225087
mouse
Strain Name:C57BL/6JSmo-Ttrtm(hTTR-V50M)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220587
mouse
Strain Name:C57BL/6JSmo-Tnfsf12/Tnfsf13tm1(hTNFSF12/hTNFSF13)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234421
mouse
Strain Name:C57BL/6JSmo-Ugt1a1tm1(hUGT1A1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232902
mouse
Strain Name:huHSC-(M-NSG)
Strain State:Repository Live | Cat. NO.:NM-NSG-017
Research Application:Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study
mouse
Strain Name:huPBMC-(M-NSG)
Strain State:Repository Live | Cat. NO.:NM-NSG-015
Research Application:Infectious disease; Gene therapy;Hematopoiesis; Drug targets without cross-reactivity; Immunogenicity study
mouse
Strain Name:C57BL/6JSmo-Vegfatm2(hVEGFA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000028
Research Application:Immunotherapy,drug screening
mouse
Strain Name:C57BL/6JSmo-Vegfatm1(hVEGFA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204984
mouse
Strain Name:C57BL/6JSmo-Vegfctm(hVEGFC)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230016
mouse
Strain Name:C57BL/6JSmo-Kdrtm2(hKDR) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00098
Research Application:Immunotherapy,cancer research,drug screening
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