The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-HA-hMYCN-IRES-BFP-Wpre-polyA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225000
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190077
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18050
Research Application：Tumor research; drug screening
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065
Disease Connection：breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-hPLA2R1-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-220264
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215002
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-PNPLA3 I148M-IRES-GFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200013
Research Application：rs738409：148 isoleucine to Methionine protein variant,I148M.Non-alcoholic fatty liver and hepatitis B cirrhosis research.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-240013
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200051
Research Application：Cancer and aging research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200052
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