The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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Strain Name：NOD-PrkdcscidIl2rg-Tg(pCMV-hIL34-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-220433
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Strain Name：C57BL/6Smoc-Tgtn(pPbsn-hMICB-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-234894
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Strain Name：C57BL/6Smoc-Tgtn(pWap-ERBB2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225013
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00081
Research Application：cancer research；Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190093
Research Application：Chemical Genetics studies.The inhibitory GiDREADD(hM4Di) could silence the activity of neurons following administration of CNO.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GqDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190106
Research Application：Chemical Genetics studies.The GqDREADD(hM3Dq) could stimulate the activity of neurons following administration of CNO.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200188
Research Application：corona virus related research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215053
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190127
Research Application：Chronic Myelocytic Leukemia(CML) research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200321
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