Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

mouse
Strain Name:BALB/cJSmo-Kdrtm2(hKDR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-232384
mouse
Strain Name:C57BL/6JSmo-Vsirtm1(hVSIR)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00118
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Vsig4tm1(hVSIG4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210004
Research Application:inmmue therapy;drug screening
mouse
Strain Name:C57BL/6JSmo-Xdhtm1(hXDH)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231913
mouse
Strain Name:C57BL/6JSmo-Xdhtm2(hXDH)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-240110
mouse
Strain Name:C57BL/6JSmo-Ighmem1Ighdem1Sirpaem1(hSIRPA)Cd47em1(hCD47)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-232159
mouse
Strain Name:C57BL/6JSmo-Itgamtm1(IRES-hCD89-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200063
mouse
Strain Name:C57BL/6JSmo-Itgamtm1(IRES-hCD89-WPRE-polyA)tm1(hIGHA1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210412
mouse
Strain Name:C57BL/6JSmo-Itgamtm1(IRES-hCD89-WPRE-polyA)Masp2tm1(hMASP2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-232115
mouse
Strain Name:C57BL/6JSmo-Mefvtm1(hMEFV-V726A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200221
Disease Connection:familial Mediterranean fever
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