Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

mouse	hTNFRSF1A Strain Name：C57BL/6JSmo-Tnfrsf1a^{tm(hTNFRSF1A)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-215017
mouse	hTNFRSF8 Strain Name：C57BL/6JSmo-Tnfrsf8^{tm(hTNFRSF8)Smoc} Strain State：Developing \| Cat. NO.：NM-HU-220202
mouse	hTNFSF11(2) Strain Name：C57BL/6JSmo-Tnfsf11^{tm1(hTNFSF11)}^Smoc Strain State：Repository Live \| Cat. NO.：NM-HU-234270
mouse	hTNFSF13B(2) Strain Name：C57BL/6JSmo-Tnfsf13b^{tm4(hTNFSF13B)}^Smoc Strain State：Developing \| Cat. NO.：NM-HU-240330
mouse	hTNFSF14 Strain Name：C57BL/6JSmo-Tnfsf14^{tm1(hTNFSF14)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-225069
mouse	hTP53(2) Strain Name：C57BL/6JSmo-Trp53^{tm2(hTP53)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-225052
mouse	hTP53-R175H Strain Name：C57BL/6JSmo-Tp53^{tm1(hTP53-R175H)}^Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-234694
mouse	hTPBG Strain Name：C57BL/6JSmo-Tpbg^{tm1(hTPBG)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-200239
mouse	hTREM2 Strain Name：C57BL/6JSmo-Trem2^{tm4(hTREM2)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-2000083 Research Application：Alzheimer's disease research;drug screening
mouse	hTREM2(2) Strain Name：C57BL/6JSmo-Trem2^{tm(hTREM2)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220502

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