In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：B6;129S-Il2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00108
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Strain Name：C57BL/6JSmo-Il20em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-231240
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Strain Name：C57BL/6JSmo-Il20raem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230353
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Strain Name：C57BL/6JSmo-Il20rbem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220394
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Strain Name：C57BL/6JSmo-Il21em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-231281
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Strain Name：C57BL/6JSmo-Il21rem2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234290
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Strain Name：C57BL/6JSmo-Il22em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220627
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Strain Name：C57BL/6JSmo-Il22ra1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200106
Research Application：Research on ERK signal transduction and Th17 cell differentiation
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Strain Name：C57BL/6JSmo-Il23aem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220628
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