Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6JSmo-Il17reem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2111298
mouse
Strain Name:C57BL/6JSmo-Il18em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231326
mouse
Strain Name:C57BL/6JSmo-Il18bpem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-241118
mouse
Strain Name:C57BL/6JSmo-Il18r1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2111655
mouse
Strain Name:C57BL/6JSmo-Il19em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230352
mouse
Strain Name:C57BL/6JSmo-Il1aem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240015
mouse
Strain Name:C57BL/6JSmo-Il1bem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231294
mouse
Strain Name:C57BL/6Smoc-Il1bosem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Il1f10em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-262439
mouse
Strain Name:C57BL/6Smoc-Il1f5em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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