Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6Smoc-Il1f8em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Il1f9em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2105611
mouse
Strain Name:C57BL/6JSmo-Il1r1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200105
Research Application:Research on Th1 differentiation pathway and hematopoietic cell lineage
mouse
Strain Name:C57BL/6JSmo-Il1r2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240877
mouse
Strain Name:C57BL/6JSmo-Il1rapem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231309
mouse
Strain Name:C57BL/6JSmo-Il1rapl1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226042
mouse
Strain Name:C57BL/6Smoc-Il1rapl2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Il1rl1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226207
mouse
Strain Name:C57BL/6JSmo-Il1rl2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2111450
mouse
Strain Name:C57BL/6Smoc-Il1rnem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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