Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6JSmo-Il23rem1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-210008
mouse
Strain Name:C57BL/6JSmo-Il24em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-242233
mouse
Strain Name:C57BL/6JSmo-Il25em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231241
mouse
Strain Name:C57BL/6JSmo-Il27em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2111431
mouse
Strain Name:C57BL/6JSmo-Il27raem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2112768
mouse
Strain Name:C57BL/6JSmo-Il2raem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-200107
Research Application:Research on GPCR and RET signal transduction
mouse
Strain Name:C57BL/6JSmo-Il2rbem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231330
mouse
Strain Name:C57BL/6JSmo-Il2rgem1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-251630
mouse
Strain Name:C57BL/6JSmo-Il3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2114434
mouse
Strain Name:C57BL/6Smoc-Il31em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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