In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6JSmo-Il33em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200108
Research Application：Studies on protein metabolism and the development and heterogeneity of the ILC family
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Strain Name：C57BL/6JSmo-Il34em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-210169
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Strain Name：C57BL/6JSmo-Il3raem(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230198
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Strain Name：C57BL/6JSmo-Il4em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220440
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Strain Name：C57BL/6JSmo-Il4i1em(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-215073
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Strain Name：C57BL/6JSmo-Il4raem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230205
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Strain Name：C57BL/6JSmo-Il5em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-231315
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Strain Name：C57BL/6JSmo-Il5raem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-231242
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Strain Name：C57BL/6JSmo-Il6em(flox)/Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-220529
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