Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

mouse
Strain Name:C57BL/6JSmo-Il16em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-220281
mouse
Strain Name:C57BL/6JSmo-Il17aem(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230191
mouse
Strain Name:C57BL/6JSmo-Il17bem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-252780
mouse
Strain Name:C57BL/6JSmo-Il17cem(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-220156
mouse
Strain Name:C57BL/6JSmo-Il17dem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-250139
mouse
Strain Name:C57BL/6JSmo-Il17fem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231320
mouse
Strain Name:C57BL/6JSmo-Il17raem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200103
Research Application:Research on ERK signal transduction and IL-17 family signal transduction pathway
mouse
Strain Name:C57BL/6JSmo-Il17rbem(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230351
mouse
Strain Name:C57BL/6JSmo-Il17rcem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200104
Research Application:Research on ERK signal transduction and TGF-β pathway
mouse
Strain Name:C57BL/6JSmo-Il17rdem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2111237
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