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HBV-Tg

Strain Name：B6.Cg-Tg(HBV)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00003
Validation Data：Presence  |  Publications：5piece

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

pTRE-Nrg1-Tg

Strain Name：C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology，this strain is Nrg1 overexpression induced by tetracycline

Disruption of imprinting and aberrant embryo development in completely inbred embryonic stem cell-derived mice

Model Organisms：小鼠 Product & Service：- Research field：Model approach

DNA methylation embryo development epigenetic genome imprinting inbred ES cell

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Model Organisms：小鼠 Product & Service：PRKAG2 H530R Research field：Heart

室性心律失常 AAV9 基因治疗

Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation

Model Organisms：Zebrafish Product & Service：- Research field：snailfish

What are genetically engineered mice?

mouse genome point mutation transgene

Enhancing Your Research: How GenoBioTX's Gene Editing Technology Empowers Research Breakthroughs

Gene editing technology GenoBioTX seminar Genome editing platform Gene regulation Gene editing techniques Biotechnology seminar Preclinical research tools.

This seminar will introduce GenoBioTX’s gene editing platform and technology, highlighting how these techniques can enhance your research projects. We will cover the history of genome editing, provide an overview of GenoBioTX’s gene editing platform and technology, and present case studies that demonstrate how our gene editing techniques can facilitate research advancements.

How do I identify the genotypes of genetically-engineered mice?

genomic DNA PCR gel electrophoresis

Does a mouse expressing the Cre gene only have a poor phenotype?

Cre activity translocation translocation meaning