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Models

About 107 results
Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

CAG-LSL-dCas9-SPH-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-LSL-dCas9-SPH)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00025

Cre-dependent SunTag-p65-HSF1 (SPH) transgenic mice were generated with piggyBac transposon system in F1 zygotes and crossed with wild type C57BL/6 mice., SPH transgenic mouse containing HA-tagged dCas9 fused with 10xGCN4, which is linked with p65-HSF1 and EGFP in tandem via P2A and T2A respectively. The transgene is driven by the ubiquitous CAG promoter and interrupted by a loxP-stop-loxP (LSL) cassette to render Cas9 expression inducible by the Cre recombinase. Expression of dCas9 can be detected using primary antibody: rabbit monoclonal antibody to HA-tag (1:1000, #3724, CST45) and secondary antibody: goat anti-rabbit Alexa Fluor 488 (1:1000, #A-11034, Thermo Fisher).

Mice

HBV-Tg

Strain Name：B6.Cg-Tg(HBV)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00003

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

Mice

CAG-GFP-Tg

Strain Name：B6.Cg-Tg(CAG-GFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00005

These mice carry enhanced green fluorescent protein gene driven by CAG promoter.

Mice

CMV-GFP-Tg

Strain Name：B6.Cg-Tg(CMV-GFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00006

These mice carry enhanced green fluorescent protein gene driven by CMV promoter.

Mice

CAG-Dre-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-Dre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00026

These transgenic mice carry Dre recombinase driven by CAG promoter.

Mice

hCEACAM5-Tg

Strain Name：C57BL/6Smoc-Tg(hCEACAM5)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-225005

These transgenic mice harbor hCEACAM5 expression cassettes.

Mice

Il1b-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-luc)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00001

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

hTNFa-Tg

Strain Name：C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200004

These transgenic mice harbor hTNFa promoter-hTNFa-pA expression cassette.

Mice

hLILRB2-hLILRB3-Tg

Strain Name：C57BL/6Smoc-Tg(loxp-LILRB2-LILRB3-FRT-PGK-PuropolyA-FRT-lox2272)
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220136

These transgenic mice harbor loxp-hLILRB2-hLILRB3-FRT-PGK-PuropolyA-FRT-lox2272 expression cassettes.

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