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Models

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Cells

MC38-hCD47-hCLDN18.2-hEGFR

Strain Name:MC38-hCD47-hCLDN18.2-hEGFR
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-S13-TM73

The MC38-hCD47/hCLDN18.2/hEGFR cell line is the MC38 colon cancer tumor cell line expressing human CD47, human CLAUDIN18.2 gene and human EGFR gene. 

Cells

NCI-H929-Luc

Strain Name:NCI-H929-Tg(luc)/Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-GS03-1

The NCI-H929-Luc cell line is derived from NCI-H929 [H929] cell line with stable and high expression of Luciferase.

Cells

KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)

Strain Name:KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)
Strain State : Validation of target gene expression completed |  Cat. NO.:NM-YD10

derived from lung cancer model of the offspring produced by mating Mki67-tdTomato-2A-Luc (NM-KI-200223) and Kras-LSL-G12D mice (NM-KI-190003) infected by AAV-Cre virus

Cells

NCI-H446

Strain Name:NCI-H446
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-FX02

The NCI-H446 cell line was derived by D. Carney, A.F. Gazdar and associates in 1982 from the pleural fluid of a patient with small cell cancer of the lung.

Cells

Trp53-KO/Kras-G12D

Strain Name:Trp53-KO/Kras-G12D
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-YD08

Trp53-KO/Kras-G12D cell line is murine cell derived from lung cancer model of the offspring produced by mating Trp53-Flox mice (NM-CKO-18005) and Kras-LSL-G12D mice (NM-KI-190003).

Cells

Panc02-Luc

Strain Name:Panc02-Tg (Luc)Smoc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-D01-2

The mouse Panc02 is a well-established mouse pancreatic epithelial cell line, derived from the adenocarcinoma model developed by chemical induction with 3-MCA (3-methylcholanthrene) in male C57BL/6 mice. The Panc02-Luc cell line is a Panc02 cell line with stable and high expression of Luciferase.

Literature

DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane

Model Organisms:Mouse Product & Service:Dhhc4.Dhhc5 Research field:metabolism

Literature

HIF-1alpha and HIF-2alpha induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide

Model Organisms:斑马鱼 Product & Service:HIF-2alpha Research field:Drug screening and drug mechanism

血管生成 Thalidomide 血管内皮生长因子 VEGF

Literature

Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo.

Model Organisms:小鼠 Product & Service:R26-CAG-LSL-RSR-tdTomato-2A-DTR Research field:DTR mice

Literature

Palladin regulates cell and extracellular matrix interaction through maintaining normal actin cytoskeleton...

Model Organisms:细胞 Product & Service:Palld Research field:Cytoskeleton

细胞外基质

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