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Models

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Mice

hIL2RB/hPD-1

Strain Name：C57BL/6Smoc-Il2rbem1(hIL2RB)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220036
Validation Data：Absence

hIL2RB(NM-HU-2000055) mice were crossed with hPD-1(NM-HU-00015) to generate hIL2RB/hPD-1 mice.

Mice

Park7-KO

Strain Name：C57BL/6Smoc-Park7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191006
Validation Data：Absence

Exon 3-5 of Park7 gene was deleted to generate Park7 knockout mice.

Mice

Rag1-2A-Cre

Strain Name：C57BL/6Smoc-Rag1em(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220088
Validation Data：Absence

2A-Cre expression cassette was knocked into the Rag1 gene stop codon site.

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tigitem1(hTIGIT) Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190029
Validation Data：Absence

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

Il1f6-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1f6em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00017
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f6.

Mice

R26-CAG-LSL-hIDH2*R172K-IRES-Luci-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190076
Validation Data：Absence

These mice harbor a CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Pnliprp1-KO

Strain Name：B6;129S-Pnliprp1tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00005
Validation Data：Absence

Exon 1 to exon 8 were replaced with Neo cassette.

Mice

Sox10-KO

Strain Name：C57BL/6Smoc-Sox10em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200645
Validation Data：Absence

Exon 4-5 of Sox10 gene was deleted to generate Sox10 knockout mice.

Mice

R26-loxP-tdTomato-loxP-DTA

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm(SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225003
Validation Data：Absence

SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA expression cassette was knocked into the the Rosa26 locus.

Mice

Gpr132-KO

Strain Name：C57BL/6Smoc-Gpr132em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200979
Validation Data：Absence

Exon 3 of Gpr132 gene was deleted to generate Gpr132 knockout mice.

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