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Models

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Mice

Slc6a1-KO

Strain Name：B6;129S-Slc6a1tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00002
Validation Data：Absence

Slc6a1-KO mice(Stock No.NM-KO-00002）carry a knockout allele derived from the targeted deletion of exon 2-3. While Slc6a1-KO(2) mice (Stock No.NM-KO-210290）carrying the exon 6 deletion. Slc6a1-KO(3) mice(Stock No.NM-KO-210126） carrying the exon 7 deletion.

Mice

Btd-KO

Strain Name：C57BL/6Smoc-Btdem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200630
Validation Data：Absence

Exon 2-3 of Btd gene was deleted to generate Btd knockout mice.

Mice

Penk-IRES-Cre

Strain Name：C57BL/6Smoc-Penkem1(IRES2-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200088
Validation Data：Presence

A IRES2-iCre expression cassette was knocked into the Penk gene stop codon site.

Mice

hPD-1/hCD28

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000097
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hCD28(NM-HU-190011) to generate hPD-1/hCD28.

Mice

Slc6a4-KO

Strain Name：C57BL/6Smoc-Slc6a4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200892
Validation Data：Absence

Exon 3-4 of Slc6a4 gene was deleted to generate Slc6a4 knockout mice.

Mice

Eno2-2A-Cre

Strain Name：C57BL/6Smoc-Eno2em1(2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200012
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Eno2 gene stop codon site.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029
Validation Data：Absence

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Mice

Tigre-TetO-hVEGFA165-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs7em(tetO-VEGFA165-IRES-EGFP-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-205000
Validation Data：Absence

tetO-VEGFA165-IRES-EGFP-polyA expression cassette was knocked into the TIGRE gene .

Mice

Prox1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Prox1em1(IRES-CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200119
Validation Data：Presence

A IRES-CreERT2-pA expression cassette was knocked into the Prox1 gene stop codon site. Prox1 encodes a transcription factor (prospero-related homeobox 1) that is necessary for the formation and maintenance of lymphatic vessels. When Prox1-IRES-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in PROX1positive cells.

Mice

hCD3EDG/hTPBG

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Tpbgem1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220111
Validation Data：Absence

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

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