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Models

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Mice

Aacs-Flox

Strain Name：C57BL/6Smoc-Aacsem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253839

These mice carry loxP sites flanking exon 2 of Aacs gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aacs gene.

Mice

Slc6a1-S295L

Strain Name：C57BL/6Smoc-Slc6a1em2(S295L)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190014
Publications：1piece

These mice carry a p.S295L mutation in Slc6a1 gene .

Mice

Slc6a3-KO

Strain Name：C57BL/6Smoc-Slc6A3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191034

Exon 4 of Slc6a3 gene was deleted to generate Slc6a3 knockout mice.

Mice

hPD-1/hPD-L1/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200267

hTIGIT（NM-HU-00053）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIGIT mice

Mice

Wdfy1-CreERT2

Strain Name：C57BL/6Smoc-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220121

Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.

Mice

Aadacl3-Flox

Strain Name：C57BL/6Smoc-Aadacl3em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253851

These mice carry loxP sites flanking exon 2-3 of Aadacl3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl3 gene.

Mice

R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190083

These mice harbor a CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

Tg-2A-CreERT2

Strain Name：C57BL/6Smoc-Tgem1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215040
Validation Data：Presence

2A-CreERT2-WPRE-polyA expression cassette was knocked into the Tg gene.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358

hSIRPA(2)(NM-HU-18015)，hCD47（NM-HU-00050), hPD-1（NM-HU-00015）, hPD-L1（NM-HU-00062）was crossed together to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1 mice.

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200169
Validation Data：Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

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