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Models

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Mice

hLY96

Strain Name：C57BL/6Smoc-Ly96tm1(hLY96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210003
Validation Data：Presence

The endogenous mice Ly96 gene was replaced by human LY96 gene

Mice

Ace2-KO

Strain Name：C57BL/6Smoc-Ace2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190906

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

Mice

Gabra1-KO

Strain Name：C57BL/6Smoc-Gabra1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190570

Exon 4 of Gabra1 gene was deleted to generate Gabra1 knockout mice.

Mice

Fgf23-R176Q

Strain Name：C57BL/6Smoc-Fgf23em1(R176Q)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200248

These mice carry a p.R176Q mutation of Fgf23 gene.

Mice

Sst-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sstem(IRES-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220108
Validation Data：Presence

IRES-CreERT2-WPRE-pA expression cassette was knocked into the Sst gene stop codon site.

Mice

hPD-1/hICOS(2)

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Icostm1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000100
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Mice

Sftpc-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sftpcem(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18020
Validation Data：Presence

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

Mice

Oprk1-2A-Cre

Strain Name：C57BL/6Smoc-Oprk1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200299
Validation Data：Presence

2A-Cre expression cassette was knocked into the Oprk1 gene stop codon site. Oprk1 (opioid receptor, kappa 1) encodes opioid receptor which was expressed in multiple brain regions. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids.

Mice

Clu-2A-DreERT2

Strain Name：C57BL/6Smoc-Cluem2(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200025
Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Clu gene stop codon site.

Mice

R26-CAG-LSL-hFGFR2*S320C-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-FGFR2(S320C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190079

These mice harbor a CAG-LSL-FGFR2(S320C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

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