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Models

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Mice

Dmp1-KO

Strain Name：C57BL/6Smoc-Dmp1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200634
Validation Data：Absence

Exon 4-6 of Dmp1 gene was deleted to generate Dmp1 knockout mice.

Mice

Ccl4-c-Rox-TGATAA-Stop-c-Rox-2A-Cre

Strain Name：C57BL/6Smoc-Ccl4em(c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225056
Validation Data：Absence

c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA expression cassette was knocked into the Ccl4 gene .

Mice

Sirt3-KO

Strain Name：C57BL/6Smoc-Sirt3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190368
Validation Data：Absence

This Sirt3 knockout mouse model was generated by knocking out the exon 2-3 region of the Sirt3.

Mice

Tfam-Flox

Strain Name：C57BL/6Smoc-Tfamtm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200173
Validation Data：Absence

These mice carry loxP sites flanking exon 10-13 of Tfam gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tfam gene.

Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007
Validation Data：Absence

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

Il1f9-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1f9em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00018
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f9.

Mice

Sst-2A-TagBFP

Strain Name：C57BL/6Smoc-Sstem(2A-TagBFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220178
Validation Data：Absence

2A-TagBFP expression cassette was knocked into the Sst gene stop codon site.

Mice

hPD-1/hSIGLEC15

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000093
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-1/hSIGLEC15.

Mice

Rbfox3-2A-DreERT2

Strain Name：C57BL/6Smoc-Rbfox3em1(2A-DreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190103
Validation Data：Presence

A 2A-DreERT2-WPRE-pA expression cassette was knocked into the Rbfox3 gene stop codon site.

Mice

Cyp19A1-KO

Strain Name：C57BL/6Smoc-Cyp19A1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2102244
Validation Data：Absence

Exon 2 of Cyp19a1 gene was deleted to generate Cyp19a1 knockout mice.

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