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Models

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Mice

Slc6a1-KO

Strain Name:B6;129S-Slc6a1tm1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-00002

Slc6a1-KO mice(Stock No.NM-KO-00002)carry a knockout allele derived from the targeted deletion of exon 2-3. While Slc6a1-KO(2) mice (Stock No.NM-KO-210290)carrying the exon 6 deletion. Slc6a1-KO(3) mice(Stock No.NM-KO-210126) carrying the exon 7 deletion.

Mice

Cela1-2A-DreERT2

Strain Name:C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190094
Validation Data:Presence  |  Publications:1piece

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

A4gnt-KO

Strain Name:C57BL/6Smoc-A4gntem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

Dbt-KO

Strain Name:C57BL/6Smoc-Dbtem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200633

Exon 2 of Dbt gene was deleted to generate Dbt knockout mice.

Mice

hIL5/hIL5R(3)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5ratm3(hIL5RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220011
Validation Data:Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220069

The Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA4 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hCTLA4(NM-HU-00014) mouse.

Mice

H11-CAG-RSR-tdTomato

Strain Name:C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18009
Publications:3piece

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111)to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

Atp4b-IRES-CreERT2(2)

Strain Name:C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-210119
Validation Data:Presence

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Lmna-c.C1827T

Strain Name:C57BL/6Smoc-Lmnatm1(G609G)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200284
Validation Data:Presence

These mice carry a G609G mutation of Lmna gene.

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