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Models

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Mice

hIL3/hCSF2

Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190065
Validation Data：Presence

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hCD3EDG/hCD40

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Cd40em1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220116
Validation Data：Absence

hCD3EDG(NM-HU-220120) mice were crossed with hCD40(NM-HU-00076) to generate hCD3EDG//hCD40 mice.

Mice

hPD-1/hPD-L1(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220142
Validation Data：Absence

hPD-1(BALB/c)(NM-HU-190079) mice were crossed with hPD-L1(BALB/c ) (NM-HU-220028) mice to generate hPD-1/ hPD-L1(BALB/c) mice.

Mice

Fas-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Fasem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191206
Validation Data：Absence

Exon 2 of Fas gene was deleted to generate Fas knockout mice.

Mice

hIL2

Strain Name：C57BL/6Smoc-Il2em3(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190048
Validation Data：Presence

The endogenous mouse Il2 gene was replaced by human IL2 gene.

Mice

Myf6-CreERT2

Strain Name：C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200125
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.

Mice

hPD-1/hLAG3/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200258
Validation Data：Absence

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hLAG3/hTIGIT.

Mice

hIL13/hOX40

Strain Name：C57BL/6Smoc-Il13em2(hIL13)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220024
Validation Data：Absence

hIL13(NM-HU-190069) was crossed with hOX40(NM-HU-00041) to generate hIL13/hOX40 mice.

Mice

hIL1RL1

Strain Name：C57BL/6Smoc-Il1rl1em4(hIL1RL1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000067
Validation Data：Presence

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

Mice

Vil1-CreERT2

Strain Name：C57BL/6Smoc-Vil1em(CreERT2)2Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225020
Validation Data：Presence

CreERT2 expression cassette was knocked into the Vil1 gene .

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