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Models

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Mice

Itgam-IRES-DTRGFP

Strain Name：C57BL/6JSmo-Itgamem1(IRES-DTR-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200066
Validation Data：Presence

A IRES-DTR-EGFP expression cassette was knocked into the Itgam gene stop codon site.

Mice

IL1B-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00001
Validation Data：Presence  |  Publications：1piece

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

hIL13/hOX40

Strain Name：C57BL/6JSmo-Il13tm2(hIL13)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220024

hIL13(NM-HU-190069) was crossed with hOX40(NM-HU-00041) to generate hIL13/hOX40 mice.

Mice

Stat3-Flox

Strain Name：C57BL/6JSmo-Stat3tm7(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200050

These mice carry loxP sites flanking exon 12-14 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene.While Stat3-Flox(in-frame mutation)(Stock No.NM-CKO-200225）mice carrying the loxP sites flanking exon 18-20 of Stat3 gene.

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

H11-pAlb-NTCP-C9-IRES-EGFP

Strain Name：C57BL/6JSmo-Igs2em1(2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200054
Validation Data：Presence

These mice harbor a 2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns cassette in the lgs2 locus generated by homologous recombination.

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Tigittm1(hTIGIT) Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190029

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

Tff1-Cre

Strain Name：C57BL/6JSmo-Tff1em(Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225005
Validation Data：Presence

Cre expression cassette was knocked into the Tff1 gene .

Mice

hDMD

Strain Name：C57BL/6JSmo-Dmdtm1(hDMD)Smoc
Strain State：Developing | Cat. NO.：NM-HU-225088

The endogenous mouse Dmd gene was replaced by human DMD gene.

Mice

Esr1-2A-Cre

Strain Name：C57BL/6JSmo-Esr1em1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200164
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Esr1 gene stop codon site.

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