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Models

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Mice

Mesp1-CreERT2

Strain Name：C57BL/6Smoc-Mesp1em(CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215087
Validation Data：Absence

CreERT2-Wpre-pA expression cassette was knocked into the Mesp1 gene .

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038
Validation Data：Absence

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

hPTGDR2

Strain Name：C57BL/6Smoc-Ptgdr2em1(hPTGDR2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225033
Validation Data：Presence

The endogenous mouse Ptgdr2 gene was replaced by human PTGDR2 gene.

Mice

hIL17RB(2)

Strain Name：C57BL/6Smoc-Il17rbem2(hIL17RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200225
Validation Data：Absence

The endogenous mice Il17rb gene was replaced by human IL17RB gene. While hIL17RB(Stock No.NM-HU-200224) mice function similarly to hIL17RB(2) mice,for more detailed information please contact our technical advisor.

Mice

Ace2-KO

Strain Name：C57BL/6Smoc-Ace2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190906
Validation Data：Absence

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

Mice

hICOS(2)

Strain Name：C57BL/6Smoc-Icosem2(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190030
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(Stock No.NM-HU-00052) mice function similarly to hICOS(2) mice,for more detailed information please contact our technical advisor.

Mice

Fgf23-R176Q

Strain Name：C57BL/6Smoc-Fgf23em1(R176Q)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200248
Validation Data：Absence

These mice carry a p.R176Q mutation of Fgf23 gene.

Mice

Upk3b-Dre

Strain Name：C57BL/6Smoc-Upk3bem1(Dre-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200175
Validation Data：Presence

A Dre-Wpre-polyA expression cassette was knocked into the Upk3b gene start codon site.

Mice

hITGAV

Strain Name：C57BL/6Smoc-Itgavem1(hITGAV)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225043
Validation Data：Absence

The endogenous mouse Itgav gene was replaced by human ITGAV gene.

Mice

hFCGR2B/hOX40

Strain Name：C57BL/6Smoc-Fcgrt2Bem2(hFCGRT2B)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200265
Validation Data：Presence

hFCGR2B（NM-HU-2000010） was crossed with hOX40（NM-HU-00041）to generate hFCGR2B/hCD40 mice

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