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Mice

Dmp1-2A-CreERT2

Strain Name:C57BL/6Smoc-Dmp1em(2A-CreERT2)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225004
Validation Data:Absence

2A-CreERT2 expression cassette was knocked into the Dmp1 gene .

Mice

Dmpk-KO

Strain Name:C57BL/6Smoc-Dmpkem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200635
Validation Data:Absence

Exon 1-7 of Dmpk gene was deleted to generate Dmpk knockout mice.

Mice

Slc17a7-IRES-Cre

Strain Name:C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200086
Validation Data:Presence

A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.

Mice

Col3a1-2A-Cre

Strain Name:C57BL/6Smoc-Col3a1em(2A-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-220106
Validation Data:Absence

2A-Cre expression cassette was knocked into the Col3a1 gene stop codon site.

Mice

Ighg1-Luc

Strain Name:C57BL/6Smoc-Ighg1em1(Luciferase)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200273
Validation Data:Absence

Luciferase expression cassette was knocked into the Ighg1 gene stop codon site.

Mice

Pgr-Cre

Strain Name:C57BL/6Smoc-Pgrem1(iCre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200117
Validation Data:Presence

A iCre-WPRE-pA expression cassette was knocked into the Pgr gene start codon site.

Mice

hNR1I3

Strain Name:C57BL/6Smoc-Nr1i3em2(hNR1I3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200253
Validation Data:Presence

The endogenous mice Nr1i3 gene was replaced by human NR1I3 gene.

Mice

Notch1-CreERT2

Strain Name:C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200122
Validation Data:Presence

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

hPD-1/hVEGFR2

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Kdrem2(hKDR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000098
Validation Data:Absence

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

Mice

Stat3-Flox(in-frame mutation)

Strain Name:C57BL/6Smoc-Stat3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200225
Validation Data:Absence

These mice carry loxP sites flanking exon 18-20 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene. The experimental strategy was designed with reference to the following publications: (PMID: 14566054; 17660847; 12571365). While Stat3-Flox(Stock No.NM-CKO-200050)mice carrying the loxP sites flanking exon 12-14 of Stat3 gene.

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