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Models

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Mice

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

hCD27(2)/hFCGR2B

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2btm2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

Mice

Abcd1-KO

Strain Name：C57BL/6Smoc-Abcd1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2106014

Exon 2 of Abcd1 gene was deleted to generate Abcd1 knockout mice.

Mice

hIL6R

Strain Name：C57BL/6Smoc-Il6ratm1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044

The endogenous mouse Il6ra gene was replaced by human IL-6R gene .

Mice

hHLA-A2.22

Strain Name：C57BL/6Smoc-H2-D1tm1(hHLA-A2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204988
Validation Data：Presence

The endogenous mice H2-D1 gene was replaced by human HLA-A2 gene.

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1tm3(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200114
Validation Data：Presence

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

hCRLF2

Strain Name：C57BL/6Smoc-Crlf2tm1(hCRLF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210028
Validation Data：Presence

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

Ifngr1/Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifngr1em1Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190425
Validation Data：Presence

This Ifngr1 and Ifnar1 double knockout strain is established by crossing Ifngr1-KO and Ifnar1-KO mice together.

Mice

a-IRES-Cre

Strain Name：C57BL/6Smoc-atm1(Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200027
Publications：1piece

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

hCD22

Strain Name：C57BL/6Smoc-Cd22tm2(hCD22)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000014
Validation Data：Presence

The endogenous mouse Cd22 gene was replaced by human CD22 gene.

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