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Models

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Mice

hCD20(2)

Strain Name：C57BL/6JSmo-Ms4a1tm3(hCD20)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200114
Validation Data：Presence

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

Aire-KO

Strain Name：C57BL/6JSmo-Aireem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2112347

Exon 8 of Aire gene was deleted to generate Aire knockout mice.

Mice

hIL17A

Strain Name：C57BL/6JSmo-Il17atm1(hIL17A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00042
Validation Data：Presence

The endogenous mouse Il17a gene was replaced by human IL17A gene.

Mice

hCCR8(2)/hTIGIT

Strain Name：C57BL/6JSmo-Tigittm3(hTIGIT)Ccr8tm3(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220073

hTIGIT(NM-HU-200244) mice were crossed with hCCR8(2) (NM-HU-2000054) mice to generate hTIGIT/hCCR8 mice．

Mice

hCEACAM5-Tg

Strain Name：C57BL/6JSmo-Tg(hCEACAM5)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225005
Validation Data：Presence

These transgenic mice harbor hCEACAM5 expression cassettes.

Mice

hCD40/h4-1BB(2)

Strain Name：C57BL/6JSmo-Cd40tm1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200256
Validation Data：Presence

hCD40(NM-HU-00076)was crossed with h4-1BB(NM-HU-190077) to generate hCD40/h4-1BB(2) mice.

Mice

H11-CAG-EGFP

Strain Name：C57BL/6JSmo-Igs2 em1(CAG-EGFP-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00066

These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.

Mice

hIL6R

Strain Name：C57BL/6JSmo-Il6ratm1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044

The endogenous mouse Il6ra gene was replaced by human IL-6R gene .

Mice

hCFB

Strain Name：C57BL/6JSmo-Cfbtm1(hCFB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000078
Validation Data：Presence

The endogenous mouse Cfb gene was replaced by human CFB gene.

Mice

hIFNGR1

Strain Name：C57BL/6JSmo-Ifngr1tm(hIFNGR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190076
Validation Data：Presence

The endogenous mouse Ifngr1 gene was replaced by human IFNGR1 gene.

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