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Models

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Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6JSmo-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029
Validation Data：Presence  |  Publications：1piece

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Slc34a1-CreERT2

Strain Name：C57BL/6JSmo-Slc34a1em1(CreERT2-SV40pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210110
Validation Data：Presence

CreERT2-SV40pA expression cassette was knocked into the Slc34a1 gene .

Mice

Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18030
Validation Data：Presence

A V5-IRES-luci-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled knockin model with V5, luciferase and EGFP fluorescent protein.

Mice

hIL2RB

Strain Name：C57BL/6JSmo-Il2rbtm1(hIL2RB)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000055
Validation Data：Presence

The endogenous mouse Il2rb gene was replaced by human IL2RB gene.

Mice

hCD47(Balb/c,2)

Strain Name：BALB/cJSmo-Cd47tm2(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210359
Validation Data：Presence

The endogenous mice Cd47 gene was replaced by human CD47 gene. While hCD47(BALB/c)(Stock No.NM-HU-2000022) mice function similarly to hCD47(BALB/c,2) mice, for more detailed information please contact our technical advisor.

Mice

hCSF2

Strain Name：C57BL/6JSmo-Csf2tm1(CSF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190046
Validation Data：Presence

The endogenous mouse Csf2 gene was replaced by human CSF2 gene.

Mice

App-KO

Strain Name：C57BL/6JSmo-Appem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190444

exon 3 of App gene was deleted to generate App knockout mice.

Mice

Acan-IRES-CreERT2

Strain Name：C57BL/6JSmo-Acanem1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200143
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Acan gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

hIL6/hIL6R

Strain Name：C57BL/6JSmo-Il6tm1(hIL6)Il6ratm1(hIL6R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190025
Validation Data：Presence

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD27(2)/hFCGR2B

Strain Name：C57BL/6JSmo-Cd27tm3(hCD27)Fcgrt2btm2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

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