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Models

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Mice

hTLR8/hPD-1

Strain Name:C57BL/6Smoc-Tlr8em2(TLR8)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200276

hTLR8(NM-HU-190044) was crossed with hPD-1(NM-HU-00015)to generate hTLR8/hPD-1 mice

Mice

hCD80

Strain Name:C57BL/6Smoc-Cd80em1(hCD80) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00074

The endogenous mouse Cd80 gene was replaced by human CD80 gene .

Mice

hCD27(2)/hFCGR2B

Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2bem2(hFCGRT2B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210405

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

Mice

Foxl1-2A-CreERT2

Strain Name:C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00135

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

Mice

Col1a2-2A-DreERT2

Strain Name:C57BL/6Smoc-Col1a2em1(2A-DreERT2-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210109

2A-DreERT2-Wpre-pA expression cassette was knocked into the Col1a2 gene .

Mice

Alb-IRES-Cre

Strain Name:C57BL/6Smoc-Albem1(IRES-iCre-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-200075

A IRES-iCre-WPRE-pA expression cassette was knocked into the Alb gene stop codon site.

Mice

hIL12A

Strain Name:C57BL/6Smoc-Il12atm3(hIL12A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000056

The endogenous mouse Il12a gene was replaced by human IL12A gene.

Mice

H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato

Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200319

A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.

Mice

hTIGIT/hTNFR2

Strain Name:C57BL/6Smoc-Tigitem3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210371

hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010)to generate hTIGIT(3)/hTNFRSF1B mice

Mice

App-KO

Strain Name:C57BL/6Smoc-Appem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190444

exon 3 of App gene was deleted to generate App knockout mice.

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