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Models

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Mice

hCD33

Strain Name：C57BL/6Smoc-Cd33tm3(CD33)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200002
Validation Data：Presence

The endogenous mouse Cd33 gene was replaced by human CD33 gene .

Mice

hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350

hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.

Mice

hIL23A

Strain Name：C57BL/6Smoc-Il23atm3(hIL23A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18030
Validation Data：Presence

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

Mice

A2ml1-Flox

Strain Name：C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253735

These mice carry loxP sites flanking exon 8-11 of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

hPDGFRA

Strain Name：C57BL/6Smoc-Pdgfratm1(hPDGFRA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200250
Validation Data：Presence

The endogenous mice Pdgfra gene was replaced by human PDGFRA gene.

Mice

Tmem119-2A-DTRGFP

Strain Name：C57BL/6Smoc-Tmem119em4(P2A-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200235

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

hFCGR2B

Strain Name：C57BL/6Smoc-Fcgr2btm3(hFCGR2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000010
Validation Data：Presence

The endogenous mouse Fcgr2b gene was replaced by human FCGR2B gene.

Mice

hSTING(BALB/c)

Strain Name：BALB/cAnSmoc-tmem173tm1(htmem173)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000049
Validation Data：Presence

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hPD-L1/hLAG3

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00137
Validation Data：Presence

hPD-L1（NM-HU-00062）was crossed with hLAG3（NM-HU-00049）to generate hPD-L1/hLAG3.

Mice

Axin2-CreERT2

Strain Name：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200109
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

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