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HBV-Tg

Strain Name：B6.Cg-Tg(HBV)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00003

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

pTRE-Nrg1-Tg

Strain Name：C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology，this strain is Nrg1 overexpression induced by tetracycline

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Disruption of imprinting and aberrant embryo development in completely inbred embryonic stem cell-derived mice

Model Organisms：小鼠 Product & Service：- Research field：Model approach

DNA methylation embryo development epigenetic genome imprinting inbred ES cell

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Model Organisms：小鼠 Product & Service：PRKAG2 H530R Research field：Heart

室性心律失常 AAV9 基因治疗

Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation

Model Organisms：Zebrafish Product & Service：- Research field：snailfish

Enhancing Your Research: How GenoBioTX's Gene Editing Technology Empowers Research Breakthroughs

Gene editing technology GenoBioTX seminar Genome editing platform Gene regulation Gene editing techniques Biotechnology seminar Preclinical research tools.

This seminar will introduce GenoBioTX’s gene editing platform and technology, highlighting how these techniques can enhance your research projects. We will cover the history of genome editing, provide an overview of GenoBioTX’s gene editing platform and technology, and present case studies that demonstrate how our gene editing techniques can facilitate research advancements.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

What are genetically engineered mice?

mouse genome point mutation transgene

How do I identify the genotypes of genetically-engineered mice?

genomic DNA PCR gel electrophoresis