Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.
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Strain Name：C57BL/6Smoc-Kcnma1em1G375RSmoc
Strain State：Repository Live | Cat. NO.：NM-KI-231806
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Strain Name：C57BL/6Smoc-Kitem2(V831M)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190023
Research Application：hematopoieticstem cell
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Strain Name：NOD-PrkdcscidKitem1(V831M)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200316
Research Application：Hematopoieticstem cell
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Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190003
Disease Connection：squamous cell carcinoma, prostate cancer, pancreatic carcinoma, neurofibromatosis, pancreatic ductal adenocarcinoma, juvenile myelomonocytic leukemia, urinary bladder cancer, ovarian cancer
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Strain Name：C57BL/6Smoc-Krastm(Rox-Stop-Rox-G12D)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210436
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Strain Name：C57BL/6Smoc-Latem1(Y136F）Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200249
Disease Connection：IgG4-related disease
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Strain Name：C57BL/6Smoc-Ldlrem1(C223R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00043
Research Application：Metabolic and cardiovascular disease research
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Strain Name：C57BL/6Smoc-Lepem(R105X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-230475
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Strain Name：BALB/cAnSmoc-Lepem(R105X)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-230476
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Strain Name：B6.129S-Leprtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00001
Research Application：Leptin resistance,insulin resistance,obesity,and type 2 diabetes etc.
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