Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

Mice
Strain Name:C57BL/6Smoc-Lmnaem1(G609G)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200284
Disease Connection:progeria
Mice
Strain Name:C57BL/6Smoc-Lrrk2em(P1446L)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-215098
Mice
Strain Name:C57BL/6Smoc-Maptem(R5H)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215099
Mice
Strain Name:C57BL/6Smoc-Mcm7em1R43QSmoc
Strain State:Developing | Cat. NO.:NM-KI-233284
Mice
Strain Name:B6;129S-Mdm4tm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00007
Mice
Strain Name:C57BL/6Smoc-Muc2em1C987YSmoc
Strain State:Repository Live | Cat. NO.:NM-KI-234203
Mice
Strain Name:C57BL/6Smoc-Mvdtm(F250S)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-210368
Mice
Strain Name:C57BL/6Smoc-Mvdem1F250SSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232327
Mice
Strain Name:C57BL/6Smoc-Myh6em1(R404Q)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215054
Mice
Strain Name:C57BL/6Smoc-Nagluem1(A198V)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232081
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