Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Gripap1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2102292
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Strain Name：C57BL/6JSmo-Grk1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200982
Disease Connection：Oguchi disease-2
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Strain Name：C57BL/6JSmo-Grk5em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2112587
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Strain Name：C57BL/6JSmo-Grk6em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2115678
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Strain Name：C57BL/6JSmo-Grm1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190588
Research Application：This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer.
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Strain Name：C57BL/6JSmo-Grm2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200239
Research Application：Therapeutic antibody target
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