Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Grm3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190589
Research Application：This gene encodes a metabotropic glutamate receptor. This receptors are linked to the inhibition of the cyclic AMP cascade。
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Strain Name：C57BL/6JSmo-Grm4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190590
Research Application：This gene encodes a metabotropic glutamate receptor. This receptors are linked to the inhibition of the cyclic AMP cascade。
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Strain Name：C57BL/6JSmo-Grm5em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190969
Disease Connection：schizophrenia
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Strain Name：C57BL/6JSmo-Grm5em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232648
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Strain Name：C57BL/6JSmo-Grm6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190591
Research Application：This gene encodes a metabotropic glutamate receptor. This receptors are linked to the inhibition of the cyclic AMP cascade。
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Strain Name：C57BL/6JSmo-Grm7em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-225032
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Strain Name：C57BL/6JSmo-Grm8em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190593
Research Application：This gene encodes a metabotropic glutamate receptor. This receptors are linked to the inhibition of the cyclic AMP cascade。
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Strain Name：C57BL/6JSmo-Grnem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201105
Disease Connection：Grn-related frontotemporal lobar degeneration with Tdp43 inclusions, nephrogenic diabetes insipidus
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Strain Name：C57BL/6JSmo-Grpem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190651
Research Application：lung, colon, stomach, pancreas, breast, and prostate cancer
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