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Models

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Mice

Tagln-CreERT2

Strain Name：C57BL/6JSmo-Taglnem(CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225006
Validation Data：Presence

CreERT2 expression cassette was knocked into the Tagln gene .

Mice

hCD55

Strain Name：C57BL/6JSmo-Cd55tm(hCD55)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215008
Validation Data：Presence

The endogenous mouse Cd55 gene was replaced by human CD55 gene.

Mice

Casp8-Flox

Strain Name：C57BL/6JSmo-Casp8em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hCXCR4

Strain Name：C57BL/6JSmo-Cxcr4tm1(hCXCR4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000081
Validation Data：Presence

The endogenous mouse Cxcr4 gene was replaced by human CXCR4 gene.

Mice

hIL2RG

Strain Name：C57BL/6JSmo-Il2rgtm1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

Mice

H11-CAG-LSL-Mycn-IRES-EGFP

Strain Name：C57BL/6JSmo-Igs2em1(CAG-LSL-HAtag-Mycn-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190084

These mice harbor a CAG-LSL-HA tag-Mycn-IRES-EGFP cassette in the lgs2 locus generated by homologous recombination.

Mice

hAPOE2

Strain Name：C57BL/6JSmo-Apoetm4(hAPOE2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190013
Validation Data：Presence

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

Mice

hCD52

Strain Name：C57BL/6JSmo-Cd52tm1(hCD52)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000058
Validation Data：Presence

The endogenous mouse Cd52 gene was replaced by human CD52 gene.

Mice

hPD-L1/hVISTA

Strain Name：C57BL/6JSmo-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hPD-L1(E3-4)

Strain Name：C57BL/6JSmo-Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039
Validation Data：Presence

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

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