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Models

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Mice

hIL12B

Strain Name：C57BL/6Smoc-Il12betm3(hIL12B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000057
Validation Data：Presence

The endogenous mouse Il12b gene was replaced by human IL12B gene.

Mice

Trp63-DreERT2

Strain Name：C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190029
Validation Data：Presence  |  Publications：1piece

A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.

Mice

hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210414
Validation Data：Presence

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

Mice

hPD-1/hPD-L1/hPD-L2

Strain Name：C57BL/6Smoc-Pdcd1lg2tm1(hPDCD1LG2)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190060

The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene.

Mice

hCEACAM5-Tg

Strain Name：C57BL/6Smoc-Tg(hCEACAM5)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225005
Validation Data：Presence

These transgenic mice harbor hCEACAM5 expression cassettes.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

Erbb2-Flox

Strain Name：C57BL/6Smoc-Erbb2em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220557

These mice carry loxP sites flanking exon 2 of Erbb2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Erbb2 gene.

Mice

Agrp-IRES-Dre

Strain Name：C57BL/6Smoc-Agrpem(IRES-Dre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220330

IRES-Dre expression cassette was knocked into the Agrp gene stop codon site.

Mice

Aire-KO

Strain Name：C57BL/6Smoc-Aireem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2112347

Exon 8 of Aire gene was deleted to generate Aire knockout mice.

Mice

Tnnt2-dCreERT2

Strain Name：C57BL/6Smoc-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

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